Thursday, October 16, 2008

FiO 08 emphasizes biomed research

I’m looking forward to next week’s Frontiers in Optics 2008 (Oct. 19-23, Rochester, NY), which is the 92nd Annual Meeting of the Optical Society (OSA). The event is logically co-located with Laser Science XXIV, the annual meeting of the American Physical Society's Division of Laser Science). It will be tough to split my time between the exhibit hall and the numerous conference sessions describing optics advances for medical research -- which the conference organizers are clearly emphasizing. Here’s a quick look at five of those presentations:

I’m looking forward to next week’s Frontiers in Optics 2008 (Oct. 19-23, Rochester, NY), which is the 92nd Annual Meeting of the Optical Society (OSA). The event is logically co-located with Laser Science XXIV, the annual meeting of the American Physical Society's Division of Laser Science). It will be tough to split my time between the exhibit hall and the numerous conference sessions describing optics advances for medical research -- which the conference organizers are clearly emphasizing. Here’s a quick look at five of those presentations:

1. Presentation FTuD3, Optical Intraoperative Measurement of Function in the Human Brain, (Tuesday, Oct. 21, 9:15 a.m.), will discuss how Paul Hoy and colleagues at the University of Southampton in England are developing a rapid and highly sensitive light-reflectance method for measuring brain function across the entire area during surgery. The team got good results when they evaluated their approach on four people undergoing brain surgery; they are now collecting data that will lead to a clinical trial.

2. Another presentation taking place at the same time will describe new optical techniques that may facilitate study of the link between altered blood flow and Alzheimer's disease (FTuE4, Femtosecond Laser-Induced Microvascular Clots Trigger Alzheimer's Disease Pathology, Tuesday, Oct. 21, 9:15 a.m). Chris Schaffer and colleagues at Cornell University use tightly focused femtosecond lasers to introduce clots in the microvasculature in the brains of rodents. The laser cuts open the cells lining the blood vessels, triggering clotting and leading to occlusion formation. Schaffer and his colleagues plan to systematically study the effect of these clots on the cognitive decline of the Alzheimer's mice.

3. Schaffer, by the way, is advisor to Cornell doctoral candidate John Nguyen, who has developed an animal model for looking at the effect of small strokes in the tiny venules in the brains of rodents. They are using a laser and nonlinear optics to target and clot vessels of the venule system and then monitor the effect on blood flow in upstream capillaries in the brain. (FTuE3, Femtosecond Laser-Driven Photodisruption to Induce Single Venule Occlusions in Rodent Brain, Tuesday, Oct. 21, 9 a.m).

4. Later that morning, researchers from the University of Michigan will reveal an optical method to detect pancreatic cancer in patients at early stages -- an advance that could greatly improve the chances of patient surviva. They are using a multimodal optical spectroscopy approach to observe reflectance and fluorescence properties of pancreatic tissue samples. Spectral analysis has shown significant differences between normal, pancreatitis (inflammation) and cancerous tissues, thus suggesting non-invasive diagnostic possibilities. That work is described in presentation FTuK5, Modeling Reflectance and Fluorescence Spectra of Human Pancreatic Tissues for Cancer Diagnostics, (Tuesday, Oct. 21, 11:30 a.m.).

5. And while the conference will feature plenty more bio research, here’s the last one I’ll cover here: University of Indiana researchers will explain a new technique using near-infrared light that allows them to see blood flow within all capillaries of the light sensitive tissues in the retina at the back of the eye (FWW6, Constructing Human Retinal Capillary Maps from Adaptive Optics SLO Imaging, Wednesday, Oct. 22, 5:15 p.m.) This patient-friendly alternative to the current unpleasant diagnostic method relies on adaptive optics combined with a confocal scanning laser opthalmoscope.

I hope to see you at the show!

More information:
Frontiers in Optics 2008

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