I was intrigued to learn about the technique developed by scientists at New York University to record 3D movies of microscopic systems, such as biological molecules, using holographic video. They describe the method, detailed in a recent Optics Express paper, as a label-free approach to flow cytometry—and say it could improve medical diagnostics and drug discovery. Then I learned of a commercial instrument claiming the same capabilities.
I was intrigued to learn about the technique developed by scientists at New York University to record 3D movies of microscopic systems, such as biological molecules, using holographic video. Researchers in Professor David Grier's lab describe the method, which they detailed in a recent Optics Express paper, as a label-free approach to flow cytometry. They say it could improve medical diagnostics and drug discovery.
Then I learned that a commercial instrument claiming the same capabilities has been in existence for more than five years. The Digital Holographic Microscope, manufactured by Lyncee Tec (Lausanne, Switzerland) and distributed in the US by NanoAndMore USA, Inc., comes in reflection mode and transmission mode models. The former has some unique features including a 25MHz stroboscopic mode that allows stop-action in the nanosecond range. It can map movement and show the influence of changing variables in real-time. "There is nothing else commercially available that can do this," NanoAndMore CEO George C. McMurtry told me. In addition, he said, the commercial instrument "does exactly what Professor David Grier’s group had to make from scratch." McMurtry added, "We are trying to get the pharmaceutical companies and university researchers to realize that this instrument exists and can greatly speed up their research efforts."
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Bioscience imaging is advancing, with new data density exponentiating progress in the research-relevant scales of pico/femtostructure which govern the quantum effects and relativistic factors of biomolecular interactions. This research augments the tissue imaging arts with refinements of those focusing mechanisms. That all depends on the atomic topological function used to model the examples.
Recent advancements in quantum science have produced the picoyoctometric, 3D, interactive video atomic model imaging function, in terms of chronons and spacons for exact, quantized, relativistic animation. This format returns clear numerical data for a full spectrum of variables. The atom's RQT (relative quantum topological) data point imaging function is built by combination of the relativistic Einstein-Lorenz transform functions for time, mass, and energy with the workon quantized electromagnetic wave equations for frequency and wavelength.
The atom labeled psi (Z) pulsates at the frequency {Nhu=e/h} by cycles of {e=m(c^2)} transformation of nuclear surface mass to forcons with joule values, followed by nuclear force absorption. This radiation process is limited only by spacetime boundaries of {Gravity-Time}, where gravity is the force binding space to psi, forming the GT integral atomic wavefunction. The expression is defined as the series expansion differential of nuclear output rates with quantum symmetry numbers assigned along the progression to give topology to the solutions.
Next, the correlation function for the manifold of internal heat capacity energy particle 3D functions is extracted by rearranging the total internal momentum function to the photon gain rule and integrating it for GT limits. This produces a series of 26 topological waveparticle functions of the five classes; {+Positron, Workon, Thermon, -Electromagneton, Magnemedon}, each the 3D data image of a type of energy intermedon of the 5/2 kT J internal energy cloud, accounting for all of them.
Those 26 energy data values intersect the sizes of the fundamental physical constants: h, h-bar, delta, nuclear magneton, beta magneton, k (series). They quantize atomic dynamics by acting as fulcrum particles. The result is the picoyoctometric, 3D, interactive video atomic model data point imaging function, responsive to keyboard input of virtual photon gain events by relativistic, quantized shifts of electron, force, and energy field states and positions.
Images of the h-bar magnetic energy waveparticle of ~175 picoyoctometers are available online at http://www.symmecon.com with the complete RQT atomic modeling manual titled The Crystalon Door, copyright TXu1-266-788. TCD conforms to the unopposed motion of disclosure in U.S. District (NM) Court of 04/02/2001 titled The Solution to the Equation of Schrodinger.
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